2015 Sponsors

Full Symposium Descriptions

Application & Instrumentation Symposia   |   Biological Sciences Symposia   |   Physical Sciences Symposia

Application & Instrumentation Symposia

A01 Vendor Symposium: New Tools for Life and Materials Sciences
Organizers: William Russin, Chris Kiely

This symposium provides an opportunity for instrument manufacturers and vendors to showcase new developments resulting in improved technology solutions. Topics include: new methods and techniques; new developments and technologies; breakthrough and new instrumentation; and improvements to existing instrumentation.

A02 TEM Phase Contrast Imaging
Organizers: Mike Marko, Radostin Danev

Conventional defocus phase-contrast imaging provides poor contrast at low resolution, and transfers information in a non-uniform manner with regard to spatial frequency. Phase plates can provide a practical solution to these problems. The theory, construction, and practical use of phase plates will be explored. In biological cryo-TEM, high-contrast, high-resolution imaging at low electron dose is facilitated. In materials science, the combination of a physical phase plate with tunable Cs offers an unparalleled opportunity for characterization of both atomic details and larger structures. The number of laboratories exploring the use of phase plates is growing, and applications in biology are soon becoming routine. This will be a timely opportunity to learn from each other.

A03 Electron Holography for Nanofields in Solids
Organizers: Hannes Lichte, Molly McCartney, Ken Harada

Conventional intensity images do not reveal the phase modulation hence are blind, e.g., for electric and magnetic nanofields. Electron holography is uniquely healing this phase loss in that it records the complete electron wave passing through the TEM specimen. Reconstructed amplitude and phase allow both atomic-scale analysis as well as measurement of nano-scale items such as electrostatic and magnetic fields. However, uniquely attributing the findings to specific object properties is an increasing challenge. This symposium will consider recent advances in electron holography techniques and applications. Platform and poster presentations will include the emergence of novel approaches and instrumentation for electron holography, as well as providing an overview of latest applications to piezoelectric and ferroelectric materials, measurement of charge, magnetic nanostructures, both natural and man-made, and dopant profiling in semiconductor devices.

A04 Advances in FIB: New Instrumentation and Applications in Materials and Biological Sciences
Organizers: Srinivas Subramaniam, Keana Scott, Lucille Giannuzzi

The recent decade has seen a renaissance in FIB instrumentation with research and development of multiple ion sources aimed at addressing a wide range of scientific issues. A broad spectrum of FIB instrumentation using Helium, Neon, Gallium, Xenon and Laser sources are available for applications ranging from high spatial resolution imaging and lithographic applications to high throughput material removal and macrofabrication, enabling researchers to probe current and emerging fields of interest.

This session will try to showcase new developments and research in FIB/Laser instrumentation with the aim of better understanding their capabilities and application sweet spot. Design, performance and practical applications in physical and biological research will be looked at while attempting to make objective comparisons between different FIB technologies. Theoretical understanding and computational modeling of limiting and enabling features of these instruments will also be discussed.

A05 Fast and Ultrafast Imaging with Electrons and Photons
Organizers: David Flannigan, Hermann Durr, Joanna Atkin

The successful development of methods for visualizing the atomic-scale nature of matter has proven to be invaluable for enhancing our understanding of structure-function relationships in biological, chemical, and materials systems. Owing to the dynamic nature of function, the advent of techniques for generating femtosecond laser pulses has now led to the emergence of new approaches for the direct elucidation of such relationships on the necessary spatiotemporal scales. This symposium will highlight imaging methodologies that have been developed for probing a variety of dynamic processes spanning a range of distance and time, from atoms to the mesoscale and from femtoseconds to milliseconds. Such methodologies will include (but are not limited to): electron-based approaches such as ultrafast and dynamic electron microscopy, photon-based approaches such as fast and ultrafast (near-field) optical and X-ray microscopies, and tip-based near-field approaches such as ultrafast STM.

A06 Advanced Analytical TEM/STEM
Organizers: Paul Kotula, Masashi Watanabe, Gerald Kothlietner

Recent innovations in STEM / TEM hardware including high-brightness guns, high-energy resolution monochromators, and collection-efficient detectors for both XEDS and EELS signals, have made analytical investigations much more powerful and reliable. Enhancement in the acquisition speed also allows us to apply tilt-series tomography with these analytical signals in reasonable times. In addition, improved analysis software, new ways in image simulation and totally new approaches such as chiral techniques, precession acquisition or the use of cathodoluminescence signals now allow obtaining more comprehensive information about materials than ever before. This session aims to review the latest scientific achievements and their impact on the field as well as new applications of analytical electron microscopy.

A07 Scanning Probe Microscopy: New Methods and Applications
Organizers: Greg D. Haugstad, Dalia G. Yablon

This symposium covers developments in scanning probe microscopy (SPM) in the areas of (i) biomedical and pharmaceutical materials; (ii) controlled environmental conditions including gas, liquid and sample temperature; and (iii) hybrid instrumentation systems that combine force microscopy with other near-field probes like SNOM and tip-enhanced Raman spectroscopy, or far-field imaging methods utilizing light or electron/ion beams. The application space for topics (i) and (ii) continues to foster new SPM-based research, given an array of heterogeneous material systems in biomed/pharma as well as many scientific issues for which environmental variables are central. Topic (iii) includes very new combination methods such as AFM/SEM or AFM/SIMS, whereas hybridization with near- and far-field light microscopy has been under continual development for more than two decades. This symposium aims to both familiarize the uninitiated and provide a forum for the exchange of ideas among experts.

A08 Advances in Qualitative and Quantitative X-ray Microanalysis: From Detectors to Techniques
Organizers: Nicholas Ritchie, Paul Carpenter, Phillipe Pinard

This session will cover the techniques of SDD EDS and WDS for quantitative analysis and focus on capabilities of scanning electron microscopy (SEM) and electron-probe microanalysis (EPMA). We invite presentations on research, technical, and applications of these analytical tools with an emphasis on how to make analysis easier, more precise and accurate, and how real-world samples can be treated.

  • Role of SDD-EDS and WDS in quantitative analysis: How should we best merge the strengths of the wavelength dispersive spectrometry (WDS) with the strengths of the SDD.
  • Role of Monte Carlo modeling in the quantification of ideal and non-ideal samples: How can we best take advantage of recent advances in CPU and GPU power and parallelism.
  • Advances in hardware and software
  • Advances in multi-beam energy analysis of bulk and thin-film samples

A09 Advances in Combining Simulation and Experiment for Materials Design
Organizers: Paul Voyles, Gianluigi Botton

Simulation plays an ever-increasing role in the quantitative interpretation of microscopy data for materials characterization, and microscopy provides essential constraints and feedback to simulations of fundamental materials structure and properties with density functional theory, molecular dynamics, and other methods. This symposium will cover advances in simulation of electron imaging, diffraction, and spectroscopy (EELS and EDS) and how those simulations can be used to increase the information obtained from electron microscopy experiments. It will also cover how microscopy can interact and be integrated with simulations for materials discovery and design across length scales, in the spirit of the Materials Genome Initiative.

A10 Advances in Electron Diffraction and Automated Mapping Techniques
Organizers: Jorg Wiezorek, Sergei Rouvimov, Ben Britton, Muriel Veron

Advances in electron diffraction and automated mapping techniques enable quantitative crystal orientation, phase, structure, strain and defect analyses. Robust automated mapping techniques and new instrumentation provide high spatial and angular resolution required to drive forward studies of exciting materials, such as nano-crystals, utilizing TEM and SEM platforms. This symposium celebrates these advances and will present state-of-the-art developments in instrumentation, methods and research applications of quantitative electron diffraction. Topics such as precession, convergent-beam, diffraction tomography, Kikuchi (EBSD) electron diffraction and electron channeling will be discussed. This will highlight new approaches to acquisition, data handling and processing to realize new insights in materials.

A11 Electron Vortex Beams and Higher-Order Beam Modes
Organizers: Benjamin J. McMorran, Juan Carlos Idrobo

Electron vortex beams, composed of free electrons with helical wavefronts possessing quantized orbital angular momentum, are a specific example of “higher-order� electron beam modes with engineered wavefront dislocations. The unique phase, coherence, and angular momentum properties of these beams hold promise for providing new contrast mechanisms in electron microscopy, and are already being used to gain new insights in electrodynamics, the evolution of quantum systems, and into the operation of the electron microscope itself. These beams can be produced in conventional electron microscopes using a variety of new experimental techniques, which themselves have uses for phase imaging and electron interferometry. This symposium will highlight recent experimental and theoretical advances in these areas, as well as opportunities for future investigations with electron vortex beams.

A12 Low Voltage Electron Microscopy
Organizers: David C. Bell, Natasha Erdman, Jingyue Liu

This symposium will cover the physical and instrumental aspects as well as the application of Low Voltage SEM, TEM and STEM. With this symposium we attempt to find out if there are optimum energies when working with beam sensitive materials and what are the limitations with respect of resolution, applicable dose, achievable contrast and specimen preparation. Use of novel electron column design, beam deceleration techniques and new detector technologies for improvements of both imaging and microanalysis at low voltages will be covered. Analytical aspects of operating at low electron energies will also be discussed. We encourage submissions from both materials science and biological perspectives.

A13 Advancing Data Collection and Analysis for Atom Probe Tomography
Organizers: Brian Gorman, R. Prakash Kolli, Richard Martens

Atom probe tomography is a rapidly advancing area of materials characterization. Hardware advancements in the recent past have allowed data acquisition from semiconductor, organic, and insulating materials, but also have illustrated difficulties in data interpretation and reconstruction. This symposium will highlight recent research focused on APT analysis of energy materials, steel nanostructures, organic materials, and oxidation and corrosion reactions. Advances in mathematical methods for data analysis as applied to these materials are able to advance the atomic scale understanding of materials science processes. Improved reconstruction research performed using correlative analyses combining APT and computational methods such as first principles, Monte Carlo simulations, and finite element methods will also be highlighted.

A14 Surface Plasmons, Cathodoluminescence, and Low-Loss EELS
Organizers: Gerd Duscher, David McComb, Ritesh Sachan, Robert Williams

Spatially resolved measurements of low energy (0-10eV) excitations can now be probed using methods such as probe microscopies, confocal methods, STEM-cathodoluminescence and monochromated EELS. Correlation of optical and electronic transitions with collective excitations such as localized surface plasmons resonances (LSPR) and phonons provides an opportunity for improved understanding of materials that are the basis of future technologies. We welcome contributions using low-loss EELS to characterize phonons, LSPRs, optical properties and low energy electronic transitions. In particular, correlative approaches using optical/electron/probe microscopies that are encouraged. Contributions that describe new instrumentation and methods such as the influence of monochromators to low-loss EELS, STEM-cathodoluminescence techniques, as well as new methods of quantification and acquisition of low-loss EELS data are anticipated as are contributions that address theory and data interpretation.

A15 Imaging Mass Spectrometry-SIMS/Imaging Mass Spectrometry-MALDI
Organizers: Joseph Dalluge, Christopher Anderton

Imaging mass spectrometry (Imaging MS) offers direct examination of chemical patterns from cells, tissues, and materials. It is accomplished by acquiring mass spectra across selected material or tissue areas. A two-dimensional image of mass spectral data for each material slice reveals the spatial distribution of chemicals at sub-micron to 100 µm resolution. Its ability to generate beautiful chemical images from a variety of surfaces makes it a seemingly ideal tool for diagnostics and histology. This symposium will cover instrumentation, strategies and applications for imaging MS. Application areas of both MALDI and SIMS imaging MS, including biomarker discovery, pharmaceutical metabolism, imaging of endogenous proteins and metabolites, compositional characterization of cell membranes, and imaging MS in art and archaeology will be showcased. These examples will demonstrate the capabilities of a range of imaging mass spectrometry technologies, including recent advances. Each platform session will consist of invited and contributed presentations with opportunities for discussion. In addition, there will be one 2-hour imaging MS poster session.

A16 Advances in Electron and Ion Scanning Microscopies
Organizers: David Joy, Brendan Griffin

Scanning ion and electron microscopies continue to develop rapidly. Neon is routinely available as an alternative to helium, for example. Detector technologies for both conventional imaging signals (SE and BSE) increase with most SEM have at least 2 or 3 SED and 2 BSED. The BSED include annular rings designs. Stage biasing is also being used more widely to enhance signal collection and improve final probe size (resolution). Of particular interest is the re-examination of origins of the signals (electrons) collected by the new detectors. We seek presentations addressing or comparing such developments; their strengths, weaknesses and applications. Invited presentations exploring the new regimes of SEM are being compiled but contributed presentations are essential.

A17 Standardization and Metrology in Electron Microscopy and Microbeam Analysis
Organizers: Dan V. Hodoroaba, Ryna B. Marinenko, Mike Matthews

Significant effort has been made in the recent two decades to the development of written standards on the measurement, parameters, methods and reference materials used in electron microscopy and microbeam analysis. Contributions of ongoing standardization projects in the technical committee ISO/TC 202 “Microbeam Analysis� and envisioned proposals will be the focus of the symposium. In addition, reports on metrological activities dealing with measurement uncertainties, e.g. intra- and interlaboratory comparisons, for quality assurance will be included. Because such a special topic is more rigorously considered just at a later career stage, the participation of young(er) scientists who could possibly bring their own ideas on how to accurately measure specific instrumental parameters or sample properties is strongly encouraged.

Biological Sciences Symposia

B01 The R.P. Apkarian Memorial Symposium on Cryo-HRSEM
Organizers: Elizabeth Wright, Cameron Ackerley

This symposium will honor the work of Robert P. Apkarian by presenting and discussing the history of and most recent work in the field of cryo-HRSEM. Many biological systems and bio-inspired materials are extremely challenging to prepare for SEM analysis because conventional preparation methods dehydrate and fix the specimens, which subsequently introduce structurally-significant artifacts. Cryo-HRSEM methods were pioneered to enable investigators to examine a broad range of materials in their bulk phase and in a near-to-native frozen-hydrated state. This symposium will cover technique development; highlight important biological findings that have been facilitated by cryo-HRSEM; and feature several future directions emerging in the field.

B02 To the Rhizosphere — and Beyond!
Organizers: Alice Dohnalkova, Marvin Whiteley

From Arabidopsis to Zaluzianskya, this symposium will cover topics in environmental, agricultural and ecosystems areas, including but not limited to the plant physiology, plant-pathogen interactions, light energy capture, and nutrient and carbohydrate transport. Fundamental and applied research in biomass crops and biofuels production, and soil conservation will be discussed. We will also focus on the belowground portion of the plants, where the interaction of roots, soil fungi and microbes occurs, resulting in carbon sequestration and mineral weathering. Presentations on advanced microscopy methods such as multimodal, multi-scale and high-speed imaging are encouraged to participate in this session.

B03 Optogenetics: Shining New Light on Neural Circuit Function
Organizers: Mark J. Thomas, Erin B. Larson

Microscopy and microanalysis studies can provide powerful constraints on the formation and processing histories of natural materials, ranging from refractory oxides to macromolecular organic polymers. Recent technical advances in analysis methods for natural materials include isotopic composition measurements at the 10 nm scale for determination of materials origin, and low voltage aberration-corrected electron microscopy for investigation of nanocarbon phases with single atom sensitivity. Papers are solicited that address these or other technical advances in microanalysis methods, and/or novel applications of established methods, for Earth and planetary materials research.

B04 Advances in Specimen Preparation and Correlative LM- EM (CLEM) of Biological Samples
Organizers: Kent McDonald, Danielle Jorgens

Embedding samples in resins is still the predominant specimen preparation procedure for electron microscopy of biological samples. While projection imaging of thin sections is the most common form of data output, exciting new technologies such as serial block face-SEM, focused ion beam-SEM, array tomography, and correlative light and electron microscopy are also generating spectacular images and 3-D models of cell structures. In the best cases some form of rapid freezing is the fixation method of choice, followed by freeze substitution and resin embedding. Topics will include: novel freezing methods, ultra-rapid freeze substitution and embedding procedures, preservation of fluorescence in polymerized resin for correlative light and electron microscopy, 3-D imaging of cells and tissues, and novel methods for preparing cells for on-section immunolabeling. Applications of these methods to wide-ranging questions in molecular, cellular, and developmental biology will be considered.

B05 3D Structures of Macromolecular Assembiles, Cellular Organelles, and Whole Cells
Organizers: Teresa Ruiz, Esther Bullitt, Melanie Ohi

We are advancing the basic understanding of 3D structures of macromolecular assemblies, viruses and cells, as well as their communication with the host environment, through advanced EM techniques and hybrid methodologies. This symposium will highlight structural and ultrastructural studies of cells, macromolecules and macromolecular assemblies using techniques including electron tomography; electron crystallography; single-particle EM analysis; EM helical reconstruction; scanning and transmission electron microscopy; atomic force microscopy, X-ray crystallography, and modeling. Topics will include cellular metabolism, cell division and protein translation; cellular and bacterial adhesion; flagellar and filopodial motility; secretion systems; cell-cell communication and cell signaling; virus structure and virus-host interactions.

B06 Deep Tissue Imaging and Light Sheet Microscopy
Organizers: Meng Cui, Liang Gao

In vivo fluorescence microscopy has revolutionized biomedical research in recent years. Two of the frontiers of the technological development are the deep tissue imaging and the high spatial-temporal resolution volumetric imaging. Various schemes have been employed to extend the imaging depth, including adaptive optics, long wavelength multi-photon excitation and optical clearing. With minimum photobleaching and phototoxicity, light sheet microscopy has emerged as a popular solution for high spatial-temporal resolution imaging. This session covers the latest progress of the two exciting research fields and provides an opportunity to germinate ideas and explore new applications.

B07 Microscopy, Microanalysis and Image Cytometry in the Pharmaceutical Sciences
Organizers: Lynn M. DiMemmo, John Bruce Green

Pharmaceutical research and development presents unique challenges that have lead to the development of highly specialized analytical methods. This symposium will present applications of microscopy associated techniques to biological and materials science problems that arise during drug discovery, vaccine research, formulation and production. Topics will include high-content/ high-throughput screening, therapeutic targets and mechanisms, pathology, foreign material (particulate and contaminant) analysis, and characterization of drug substance and drug product. Contributed papers for platform or poster presentation on related topics are also welcome.

B08 Dynamic Fluorescence Microscopy
Organizers: Michelle Digman, Alan F. "Rick" Horwitz

The ability to detect molecular interactions in live cellular systems has been evolving over the past decade through the advancement of fluorescene correlation spectroscopy (FCS) techniques. Most recently the use of laser scanning and light sheet imaging microscopes, has led to the development of fluorescence imaging correlation microscopy techniques and 3D particle tracking allowing access to spatio-temporal information of fluorescently tagged molecules in living cells. Improvements on super-resolution microscopy approaches have also been developed to monitor molecular dynamics at a high spatial scales. This session will focus on the latest developments which are able to detect protein-protein interactions, molecular aggregation dynamics as well as mapping diffusion, flows and velocity.

B09 Utilizing Microscopy for Research and Diagnosis of Diseases in Humans, Plants, and Animals
Organizers: W. Gray Jerome, Jon Charlesworth, Gang Ning, Betty Johns

Microscopy is not only useful but critically important in the ongoing research, detection, diagnosis and treatment of disease. Advances that improve rapid and accurate detection and treatment often involve the use of various microscopic techniques. These varied techniques provide us with an improved ability to diagnose and research the origins, development and response of diseases in human, plant and animal specimens. This is an opportunity to share information on the investigation of pathogenic cells, tissues and entire organisms in clinical, diagnostic and research laboratories. Emphasis will be placed on using latest microscopy in both clinical and research laboratories.

B10 Multiscale Biological Imaging: From Micro to Macro — Animal to Clinical Models
Organizers: Kevin Eliceiri, David Entenberg

The ability to understand modern biological or medical phenomena be it the conformational dynamics of proteins, cellular division or tumor progression requires sophisticated methods that would allow interrogation in a variety of environments across multiple time and size scales. Imaging is the method of choice, but its success requires the ability to not only image the structure, but also the associated electronic, magnetic, optical, chemical and behavioral properties. There are great challenges and opportunities of scale in imaging, not only in spatial and temporal but non-spatial dimensions.

Physical Sciences Symposia

P01 Bringing the Real World into the Electron Microscope: Peter R. Swann Memorial Symposium on In situ TEM and STEM
Grace Burke, Ondrej Krivanek, Peter Crozier

Peter Swann had a huge impact on TEM and materials science with his many outstanding contributions. He designed over 600 pioneering instruments, including a differentially-pumped gas reaction cell that brought the "real world" inside the electron microscope. With his brother Rex, Peter founded Gatan, which introduced in-situ cooling/heating, imaging of cryo-transferred samples, many new TEM specimen preparation tools, EELS as a popular analytical technique, CCD cameras and digital TEM imaging, among others. Dr. Swann died in 2013. This symposium will honor his legacy by soliciting papers in the fields he pioneered, with particular emphasis on in-situ TEM and STEM.

P02 Materials Problem Solving with Aberration-Corrected EM
David Smith, Lena Kourkoutis, Jian-Min Zuo

Aberration-corrected instruments nowadays produce striking pictures of carefully chosen test objects, and information-rich images and spectra are readily obtained. However, providing meaningful solutions to ‘Real-World' problems is a continuing challenge. The goal of this symposium is to bring technical experts together with existing and potential users of AC-TEMs and AC-STEMs, in particular to illuminate the path towards practical materials problem solving using these sophisticated (and expensive) machines. Successful applications will be featured, while further topics of interest include improvements to instrumentation, practical aspects of specimen preparation, data acquisition, and artifacts, and extracting quantitative information about atomic column positions, identity and bonding environment using modeling and simulations.

P03 Advances in Microanalysis of Earth and Planetary Materials
Rhonda Stroud, Eve L. Berger

Microscopy and microanalysis studies can provide powerful constraints on the formation and processing histories of natural materials, ranging from refractory oxides to macromolecular organic polymers. Recent technical advances in analysis methods for natural materials include isotopic composition measurements at the 10 nm scale for determination of materials origin, and low voltage aberration-corrected electron microscopy for investigation of nanocarbon phases with single atom sensitivity. Papers are solicited that address these or other technical advances in microanalysis methods, and/or novel applications of established methods, for Earth and planetary materials research.

P04 Nano-characterization of Low Dimensional Materials: Carbon to 2D TMDs
Moon Kim, Zonghoon Lee, Quentin Ramasse

New materials and devices can lead to disruptive advances in nano-electronics, energy and environment-related areas. For example, carbon-based materials and devices have made significant progresses, and yet still more to be accomplished. Advent of recent 2D transition metal dichalcogenides is stimulating new applications in many new areas. This symposium will focus on analytical transmission electron microscopy techniques, aberration-correction, spectroscopy, and in-situ methods to characterize these emerging low dimensional materials of interest. Presentations are sought from the areas of nanoparticles, nanowires and nanotubes, growth morphology of various 2D materials, defects and healing of defects, interfaces, and new and emerging devices.

P05 Nuclear and Irradiated Materials: Fundamental Defect Properties
Chad M. Parish, Khalid Hattar, Arthur T. Motta

Materials in fission, fusion, accelerator, or space environments are subjected to irradiation and undergo compositional and structural evolution as a result. Because damage cascades and transmutation are atomistic processes, understanding and predicting the changes in properties and performance in radiation environments require atomistic and microstructural tools. Radiation environments vary from low temperatures, high energy, and low flux environments often found in space applications, to neutron damage of liquid helium-cooled superconductors and 1200°C tungsten under helium and neutron bombardment in fusion reactors. Modern tools provide the means to study the smallest defects at the atomic scale and the real-time evolution of radiation damage. Coupling these techniques with modeling can enable the understanding to be extended from nm through mm or larger. This symposium aims to bring together instrumentation, modelling, and applications in materials for radiation environments.

P06 Failure Analysis Applications of Microanalysis, Microscopy, Metallography, and Fractography
Daniel Dennies, William Kane

This symposium is intended to be a forum for the exchange of information and knowledge regarding the use of microanalysis, microscopy, metallography and fractography in materials-related failure analysis. Invited papers would include those involving failure investigations where microstructures, metallography and fractography are critical to identifying the root cause. Of particular interest are unique, innovative, and/or challenging applications of microscopy, metallography, fractography, and sample preparation in failure analysis. Target attendees will include engineers and scientists from all levels of analytical expertise and all related backgrounds, not just materials engineers.

P07 Metallography and Microstructural Characterization of Metals
George Vander Voort, James E. Martinez

The realm of materials science offers many challenges for revealing and characterizing microstructures of metals. The art and science of metallography continue to meet these challenges with new automated techniques for new materials and traditional engineering alloys. This symposium will cover all aspects of specimen preparation for metals, microelectronics, and virtually any other material, as they influence characterization techniques. Contributions are welcome for all specimen preparation methods, not solely mechanical grinding/polishing, such as ion-beam techniques. The effects of specimen preparation on revealing and characterizing microstructure will be highlighted in this symposium, including applications of light microscopy, quantitative metallography and image analysis, micro- and nano-indentation hardness, SEM imaging, EBSD or EDS, and any other relevant method.

P08 Microscopy and Characterization of Ceramics, Polymers and Composites
Andre Mkhoyan, Jong Seok Jeong, Laxmikant Saraf

This symposium will cover application of analytical scanning and transmission electron microscopy and spectroscopy on variety of ceramic, polymer and composite materials. While in recent years substantial advances are made in higher special and energy resolution instrumentations, many new phenomena in materials are still remained to be discovered by use of these microscopes. Therefore, in particular, contributions that show successful implementations of aberration-corrected STEM combined with high sensitivity X-ray or electron energy-loss spectroscopy to study and characterize such ceramic, polymer and composite materials are welcomed.

P09 Microscopy of Additive Manufacturing and 3D Printing in Materials and Biology
John Porter, John Wooten, Jay Potts

Additive manufacturing/3D printing encompasses multiple methods for building parts directly from feedstock such as powders, wires, and biomaterials with only minimal or no post build machining to produce a final shape. Resultant microstructures can be unique to the process and properties can be strongly dependent on such microstructures. In recent years, technologies have been developed for the additive manufacturing of polymers, metals, and ceramics. Processes include layer-based processes as well as spray processes for repair of worn parts. More recently, biological and medical opportunities have sprung up taking advantage of 3D bioprinting. Heart valves, blood vessels and whole organs have begun to be manufactured. Each of these processes brings unique challenges to build parts and tissues that meet specifications and biocompatibility. Papers are sought highlighting additive manufacturing and 3D printing in all areas of science from materials and ceramics to biology and medicine.

P10 Microscopy and Microanalysis for Real-World Problem Solving
Elaine Schumacher, Janet Woodward, Stuart McKernan, Ke-Bin Low

Microscopy and microanalysis of real-world samples present special challenges. Non-ideal samples may not lend themselves to established methodologies for preparation and analysis. Sample amounts and background information about the materials and the problem may be limited, and the time frame for producing results may be short. This symposium will focus on ways in which microscopists and Microanalysts develop unique and creative solutions for sample preparation, data acquisition and analysis, providing meaning results to solve problems in the real world.

P11 Advances in Transmission Electron Microscopy and Spectroscopy of Energy-Related Materials
Chongmin Wang, Raymond Unocic, Arda Genc

The key challenges for imaging and spectroscopy study of energy materials are twofold: (1) Probing the structure and chemistry of energy related materials at high spatial resolution and sensitivity, (2) Real time observation of the structural and chemical evolution of the material under dynamic operating condition. We have witnessed dramatic progress along these directions, such as direct atomic resolution imaging of lithium and oxygen ions using ABF imaging, advances in chemical analysis using high efficient XEDS and EELS and in-situ to operando TEM studies of catalytic reactions in gas environment, electrodes during electrochemical charge and discharge for Li ion batteries, and the nucleation and growth of nanoparticles in liquids. It is anticipated that this symposium will provide an outstanding opportunity for participants to exchange ideas and promote discussions on recent advances in the field of using TEM and STEM imaging and spectroscopy method for energy related materials.

P12 Advanced Microscopy and Microanalysis of Soft and Hybrid Nanomaterials
Jihua Chen, Honggang Cui

This symposium is focused on the use of cutting-edge microscopy and microanalysis techniques to characterize synthetic or naturally occurring nanomaterials, relevant to important applications in energy-related and biomedical/biological research. The techniques include, but are not limited to cryo-TEM, low-dose high-resolution TEM, energy-filtered TEM, STEM, X-ray microscopy, X-ray and neutron scattering. Of particular interest is the use of these state-of-art instrumentations to investigate emerging nanomaterials, ranging from organic semiconductors, polymeric materials, biomimetic or bioinspired materials, to inorganic nanoparticles and hybrid nanomaterial systems. We welcome contributions that report on ether new technique advances or novel applications of microscopy and microanalysis tools.