2015 Sponsors

Plenary Session

Oregon Convention Center, Oregon Ballroom


Professor Roger Y. Tsien, University of California — San Diego
"New Molecular Tools for Light and Electron Microscopy"

Dr. Roger Y. Tsien is best known for designing and building molecules that either report or perturb signal transduction inside living cells. These molecules, created by organic synthesis or by engineering naturally fluorescent proteins, have enabled many new insights into signaling. Extension of these methods to electron microscopy aims to reveal biochemistry at nanometer resolution. At mm-cm scales, he is exploiting new ways to target contrast agents and therapeutic agents to tumors and sites of inflammation based on their expression of extracellular proteases, and to highlight peripheral nerves to aid surgery. Also he is testing the hypothesis that life-long memories are stored as the pattern of holes in the perineuronal net, a specialized form of extracellular matrix deposited around selected neurons during critical periods of brain development.

Dr. Tsien is an Investigator of the Howard Hughes Medical Institute and Professor in the Depts. of Pharmacology and of Chemistry & Biochemistry. Honors include the Artois-Baillet-Latour Health Prize (1995), Gairdner Foundation International Award (1995), Award for Creative Invention from the American Chemical Society (2002), Heineken Prize in Biochemistry and Biophysics (2002), Wolf Prize in Medicine (shared with Robert Weinberg, 2004), Rosenstiel Award (2006), E.B. Wilson Medal of the American Society for Cell Biology (shared with M. Chalfie, 2008), and Nobel Prize in Chemistry (shared with O. Shimomura and M. Chalfie, 2008). Dr. Tsien is a member of the National Academy of Sciences and the Royal Society.


The M&M 2015 Program Committee is pleased to announce that one of three NASA astronauts will be giving a talk about onboard microscopy in spaceflight. Due to mission scheduling, the exact speaker will be determined closer to the meeting dates. Stay tuned for this exciting addition to the program!

The spaceflight environment remains one of discovery on scales large and small. Since the US Skylab orbital station, when onboard microscopy was used inflight to examine bacterial and fungal growth, many diverse samples have been microscopically analyzed both inflight and following return to Earth by state of the art facilities. These samples have included microbiological analysis of organisms and cabin atmospheric dust particles for environmental monitoring, human, animal, and plant tissue analysis examining the many changes occurring during adaptation to weightlessness, and external structures analysis for the response of materials to the harsh space environment. Onboard microscopy has taken a significant step forward with the deployment of the Light Microscopy Module on the International Space Station. Future exploration missions back to the moon and to Mars will certainly involve onsite microscopy for field sample examination for mineralogical and possible biologic analysis.